MovDisordV3, Main, Exploration, bibRecord, 002E93

Diffusion‐weighted imaging study of patients with essential tremor

Identifieur interne : 002E93 ( Main/Exploration ); précédent : 002E92; suivant : 002E94

Diffusion‐weighted imaging study of patients with essential tremor

Auteurs : Paolo Martinelli [Italie] ; Giovanni Rizzo [Italie] ; David Manners [Italie] ; Caterina Tonon [Italie] ; Fabio Pizza [Italie] ; Claudia Testa [Italie] ; Cesa Scaglione [Italie] ; Bruno Barbiroli [Italie] ; Raffaele Lodi [Italie]

Source :

Movement Disorders [ 0885-3185 ] ; 2007-06-15.

RBID : ISTEX:D7A20BE7828EE8391AF77CD53430AE61405865CA

Descripteurs français

Pascal (Inist)
- Cervelet, Coefficient diffusion, Homme, Imagerie de diffusion, Système nerveux pathologie, Tremblement.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Adult, Age of Onset, Aged, Brain (pathology), Cerebellum, Diffusion Magnetic Resonance Imaging (methods), Diffusion coefficient, Diffusion imaging, Essential Tremor (diagnosis), Essential Tremor (epidemiology), Female, Human, Humans, Male, Middle Aged, Nervous system diseases, Severity of Illness Index, Tremor, apparent diffusion coefficient, cerebellum, diffusion‐weighted imaging, essential tremor, neurodegeneration.
MESH :
- diagnosis : Essential Tremor.
- epidemiology : Essential Tremor.
- methods : Diffusion Magnetic Resonance Imaging.
- pathology : Brain.
- Adult, Age of Onset, Aged, Female, Humans, Male, Middle Aged, Severity of Illness Index.

Abstract

The pathophysiology of essential tremor (ET) is unknown. PET and fMRI studies have revealed bilateral activation and 1H‐MRS studies metabolic abnormalities in the cerebellum and other functionally related brain structures in ET. Diffusion‐weighted imaging (DWI) was used to search for evidence of tissue integrity abnormalities in these areas in ET patients and 10 matched controls by calculating water apparent diffusion coefficients (ADCs). Regions of interest included the left and right cerebellum, red nucleus, thalamus, caudate, putamen, pallidum, and frontal white matter. Histograms of ADCs were generated for all pixels in the infratentorial compartment and manually segmented areas corresponding to brainstem, vermis, and cerebellar hemispheres. ADC values were similar in all brain areas in patients and controls. Our study did not detect changes affecting the investigated brain regions in ET patients. These findings argue against major structural damage in the ET brain, although more subtle neurodegenerative changes cannot be ruled out. © 2007 Movement Disorder Society

Url:

https://api.istex.fr/document/D7A20BE7828EE8391AF77CD53430AE61405865CA/fulltext/pdf

DOI: 10.1002/mds.21287

Affiliations:

Le document en format XML

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<author><name sortKey="Rizzo, Giovanni" sort="Rizzo, Giovanni" uniqKey="Rizzo G" first="Giovanni" last="Rizzo">Giovanni Rizzo</name>
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<author><name sortKey="Manners, David" sort="Manners, David" uniqKey="Manners D" first="David" last="Manners">David Manners</name>
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<author><name sortKey="Tonon, Caterina" sort="Tonon, Caterina" uniqKey="Tonon C" first="Caterina" last="Tonon">Caterina Tonon</name>
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<author><name sortKey="Pizza, Fabio" sort="Pizza, Fabio" uniqKey="Pizza F" first="Fabio" last="Pizza">Fabio Pizza</name>
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<front><div type="abstract" xml:lang="fr">The pathophysiology of essential tremor (ET) is unknown. PET and fMRI studies have revealed bilateral activation and 1H‐MRS studies metabolic abnormalities in the cerebellum and other functionally related brain structures in ET. Diffusion‐weighted imaging (DWI) was used to search for evidence of tissue integrity abnormalities in these areas in ET patients and 10 matched controls by calculating water apparent diffusion coefficients (ADCs). Regions of interest included the left and right cerebellum, red nucleus, thalamus, caudate, putamen, pallidum, and frontal white matter. Histograms of ADCs were generated for all pixels in the infratentorial compartment and manually segmented areas corresponding to brainstem, vermis, and cerebellar hemispheres. ADC values were similar in all brain areas in patients and controls. Our study did not detect changes affecting the investigated brain regions in ET patients. These findings argue against major structural damage in the ET brain, although more subtle neurodegenerative changes cannot be ruled out. © 2007 Movement Disorder Society</div>
</front>
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Movement Disorders (revue)

Diffusion‐weighted imaging study of patients with essential tremor

Diffusion‐weighted imaging study of patients with essential tremor

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.